Image Question-27


What is the diagnosis of Histopathology Image ?


Histopathology of colloid goiter
Mikael Häggström, M.D. Author info – Reusing images- Conflicts of interest:  NoneMikael Häggström, M.D., CC0, via Wikimedia Commons

What is the diagnosis of Histopathology Image ?


A. Corpora amylacea

B. Colloid Goitre

C. Thymoma

D. Oligodendroglioma




In shorts


  • In normal thyroid gland or more commonly in hyperplastic conditions of thyroid gland such as nodular/multinodular goiter, adenomatoid goiter, or adenomatous hyperplasia, microscopically dilated thyroid follicles lined by cuboidal cells and filled with colloid may be seen.

  • When colloid secretion increases in the small secondary follicles, their mass bulges into the follicular cavity and gives rise to a “Sanderson Polster” seen at one pole along the follicular wall of enlarged and dilated follicles.

  • These dilated follicles are usually 2–3 times larger than the surrounding follicles

  • Sanderson’s polster is composed mainly of small follicles lined by cuboidal cells

What is ‘Sanderson Polster’ ?

When colloid secretion increases in the small secondary follicles, their mass bulges into the follicular cavity and gives rise to a “Sanderson Polster” seen at one pole along the follicular wall of enlarged and dilated follicles.



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