Brockenbrough-Braunwald-Morrow sign

Brockenbrough-Braunwald-Morrow sign seen in

[A] Tetralogy of Fallot
[B] Mitral Valve Prolapse
[D] Pericardial Tamponade

Brockenbrough-Braunwald-Morrow sign

Published in Methodist DeBakey Cardiovascular Journal 2014 – Alejandro TrevinoJ. Buergler

All of the following are TRUE EXCEPT for the phenomena in above image

[A] Post PVC beat there is Paradoxical decline in arterial pulse pressure
[B] Post PVC Concomitant fall in left ventricular systolic pressure
[C] Seen in HOCM
[D] Post ectopic beat vigorous contraction increases the systolic obstruction and lowers systolic pressure

Mechanism of Brockenbrough-Braunwald-Morrow sign

Ectopic atrial and ventricular beats

  • Ectopic atrial and ventricular beats are associated with a prolonged compensatory pause.
  • During this pause, more extracellular calcium enters the cardiac muscle cells and gets stored in the sarcoplasmic reticulum.
  • Increased concentrations of calcium in myocardial cells cause hypercontractility.
  • This leads to a higher systolic and pulse pressure in normal hearts.

In HOCM – vigorous contraction in the post ectopic beat

  • Increases  the  systolic obstruction
  • Lowers systolic pressure and pulse pressure

    Subscribe Medicine Question BankWhatsApp Channel

    FREE Updates, MCQs & Questions For Doctors & Medical Students

      Medicine Question Bank
      Enable Notifications OK No thanks