Ghost cells

Ghost cells generally lack nuclear and cytoplasmic details and are characteristically seen in All of the following EXCEPT

[A] Calcifying cystic odontogenic tumor
[B] Craniopharyngiomas
[C] Giant cell tumor
[D] Pilomatricomas

What is a ‘Ghost cell’?

▪️There is cell death with retainment of cellular architecture
▪️Ghost cells indicate coagulative necrosis
▪️They are dead cells

They are found in:

▪️Craniopharyngioma (Rathke pouch)
▪️Ameloblastic fibroma
▪️Calcifying odontogenic cyst (Gorlin cyst)

Infarcted Lymph Node – Ghost cells

  • Usually result of involvement by lymphoma
  • Vascular occlusion may explain necrosis
  • Outlines of necrotic lymphoma cells (“ghost cells”)

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