Cell cytoplasm has “foamy” appearance

Which cell cytoplasm has “foamy” appearance?

[A] Mast cell
[B] Osteoclast
[C] Langhans giant cells
[D] RBCs in Babesiosis

Osteoclasts – cytoplasm with a homogeneous, “foamy” appearance.
Cause – high concentration of vesicles and vacuoles.

Giant osteoclasts are seen in

[A] Tuberculosis
[C] Paget’s disease of bone
[D] Osteosarcoma

Giant osteoclasts can occur in
▪️Paget’s disease of bone
▪️Bisphosphonate toxicity [Long term Therapy]

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