What is the diagnosis of the cell shown in Image?
B. Cart Wheel cell
C. Flame cell
D. Mott Cell
Flame cells are atypical plasma cells with irregular cytoplasmic projections that stain bright purple-red with Wright-Giemsa stain.
They are usually associated with IgA myeloma
May be seen in other conditions-
- Non-IgA myelomas
- Reactive plasmacytosis
What is the cause of characteristic staining of ‘flame cell’?
The characteristic staining – related to the high carbohydrate content of IgA molecules.