Question Bank


Burns

All are true of carbon monoxide poisoning except A. Death occurs with carboxyhemoglobin concentrations around…

Oncology MCQs-1

Ann Arbor classification is for

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Most significant risk factor for cancer overall is

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Most significant risk factor for cancer overall is age; two thirds of all cases were in those aged >65 years

Cancer is the second leading cause of death behind

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heart disease

Which of the following is standard way of measuring the ability of cancer patients to perform ordinary tasks?

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Standard way of measuring the ability of cancer patients to perform ordinary tasks


Karnofsky performance status

RECIST Criteria for Solid Tumours progressive disease is defined as the appearance of any new lesion or an increase of ------- in the sum of the products of the perpendicular diameters of all measurable lesions

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>25% Response Evaluation Criteria In Solid Tumours - RECIST Criteria Progressive disease is defined as the appearance of any new lesion or an increase of >25% in the sum of the products of the perpendicular diameters of all measurable lesions


or an increase of 20% in the sums of the longest diameters by RECIST.

Most common cause of cancer death in the world

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Dukes classification is for

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Dukes classification


colorectal cancers

Calcitonin used diagnostically as a tumor marker for

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Patients with calcitonin levels >100 pg/mL have a high risk for medullary thyroid carcinoma (~90%–100%),

Which of the following tumor is least likely to be disseminated at presentation?

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Hematopoietic tumors such as leukemia, myeloma, and lymphoma are often disseminated at presentation and do not spread like solid tumors

Most common cancer

Correct! Wrong!

Lung cancer

Lung cancer

Which Adenocarcinoma of lung is most aggressive?

Correct! Wrong!

lepidic subtype is associated with good prognosis, acinar and papillary subtypes show intermediate prognosis, whereas micropapillary and solid subtypes correlate with the worst prognosis

Leading cause of cancer death

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carcinoma lung


lung cancer is the most diagnosed type of cancer, and the leading cause of cancer death

Horner's syndrome is common in lung tumors at

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Apex


Horner's syndrome - seen in Pancoast tumor which is a tumor of the apex of the lung.

Most common symptom of carcinoma lungs

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Cough

CK7 is present in many lung cancers, but absent from

Correct! Wrong!

squamous cell carcinomas.


Adenocarcinomas tend to express Napsin-A and TTF-1; squamous cell carcinomas lack Napsin-A and TTF-1, but express p63 and its cancer-specific isoform p40

"Driver mutations" – are particularly common in adenocarcinomas

Correct! Wrong!

Adenocarcinoma

Most common with carcinoma lung

Correct! Wrong!

Hypercalcemia


Most common is hypercalcemia caused by over-production of parathyroid hormone-related protein or parathyroid hormone.

Which Adenocarcinoma of lung is least aggressive?

Correct! Wrong!

lepidic type adenocarcinoma - grow along the alveolar walls


lepidic subtype is associated with good prognosis, acinar and papillary subtypes show intermediate prognosis, whereas micropapillary and solid subtypes correlate with the worst prognosis

Small cell lung cancer are most commonly found near

Correct! Wrong!

center of the lung


SCLC tumors are often found near the center of the lungs, in the major airways

Which of the following tumor develops hollow cavity and associated cell death at the center of the tumor?

Correct! Wrong!

Squamous-cell carcinoma


Squamous-cell carcinoma causes about 30% of lung cancers. Occur close to large airways. Hollow cavity commonly found at the center of the tumor.

Pathology Flash Cards-1

Lung cancers % in active smokers or those who stopped recently

Lung cancers % in active smokers or those who stopped recently
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80% of lung cancers occur in active smokers or those who stopped recently

Commonest type of carcinoma lungs

Commonest type of carcinoma lungs
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Adenocarcinoma ------ Adenocarcinoma (38%)
• Squamous cell carcinoma (20%)
• Small cell carcinoma (14%)
• Large cell carcinoma (3%)
• Other (25%)

Most common cause of cancer mortality worldwide

Most common cause of cancer mortality worldwide
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Lung cancer

Carcinoma lungs in women and nonsmokers

Carcinoma lungs in women and nonsmokers
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women and nonsmokers - adenocarcinomas are the most common cancers

Which type of peripheral neuropathy occurs in carcinoma lungs?

Which type of peripheral neuropathy occurs in carcinoma lungs?
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peripheral neuropathy - usually purely sensory

Which is the most frequent malignancy in individuals exposed to asbestos

Which is the most frequent malignancy in individuals exposed to asbestos
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Lung cancer

Which type of lung carcinoma shows the strongest association with smoking?

Which type of lung carcinoma shows the strongest association with smoking?
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Small cell carcinoma shows the strongest association with smoking

Most frequently diagnosed major cancer in the world

Most frequently diagnosed major cancer in the world
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Lung cancer

Pancoast tumors

Pancoast tumors
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Apical lung cancers in the superior pulmonary sulcus tend to invade the neural structures
Severe pain in the distribution of the ulnar nerve
Horner syndrome (enophthalmos, ptosis, miosis, and anhidrosis) on the same side as the lesion

Lung Cancer in Never Smokers.

Lung Cancer in Never Smokers.
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The WHO estimates that 25% of lung cancer worldwide occurs in never smokers

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Neuroanatomy Flash Cards-2

Kayser–Fleischer (KF) rings

Kayser–Fleischer (KF) rings are seen in which conditions?
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Kayser–Fleischer (KF) rings are a common ophthalmologic finding in patients with Wilson disease

Brushfield spots

Brushfield spots
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Brushfield spots on the iris due to Down’s syndrome

Krückmann-Wolfflin bodies

Krückmann-Wolfflin bodies
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Krückmann-Wolfflin bodies
Similar spots seen in iris like Brushfield spots Found in individuals without Down syndrome.
Krückmann-Wolfflin bodies- these spots typically are less well defined, fewer in number and more peripherally located than the Brushfield spots of trisomy 21.

Filum terminale

Filum terminale is about ----------- cm in length
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Filum terminale is about 20 cm in length

Kayser–Fleischer rings and impairment of vision

Kayser–Fleischer rings and impairment of vision
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Kayser–Fleischer rings do not cause any impairment of vision

Lisch nodules

What are 'Lisch nodules ' ?
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Lisch nodules- iris hamartomas pathognomic markers of neurofibromatosis type 1 (NF1)
Rarely seen in individuals without NF1 like segmental neurofibromatosis and Watson syndrome.

Dentate ligament

What is dentate ligament?
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Dentate ligament - dentate ligaments extend along the lateral surface of the spinal cord, between the anterior and posterior nerve roots, from the pia to the dura mater

What is the pathophysiology of Kayser–Fleischer rings ?

How the Kayser–Fleischer rings are formed ?
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Kayser–Fleischer rings are dark rings that appear to encircle the iris of the eye. They are due to copper deposition in part of the Descemet's membrane as a result of liver diseases

Is Kayser–Fleischer rings is specific to Wilson disease ?

Is Kayser–Fleischer rings is specific to Wilson disease ?
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KF rings are not specific to Wilson disease alone, they are also seen in other chronic cholestatic disorders such as primary biliary cholangitis and children with neonatal cholestasis

What happens to Kayser–Fleischer rings after treatment?

What happens to Kayser–Fleischer rings after treatment?
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Kayser–Fleischer rings- disappear with treatment and reappear with disease progression.

Sunflower cataract

Sunflower cataract
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Ocular signs of Wilson disease
Sunflower cataract and KF rings.

Schirmer's test

What is Schirmer's test ?
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Schirmer's test -Record measurement of tear secretion in patients with suspected 'dry eyes'.

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Hingorani sign

Hingorani Sign Definition: The Hingorani sign refers to dorsal foot pain reproduced on passive plantar…

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