Granulosa cell tumors

Granulosa cell tumors

  1. Call–Exner bodies
  2. “coffee-bean” nuclei
  3. estrogen secreting tumors
  4. Biomarker for granulosa cell tumours – Inhibin [hormone]

Call–Exner bodies

  1. gives a follicle-like appearance
  2. small eosinophilic fluid-filled punched out spaces between granulosa cells.
  3. They are pathognomonic for granulosa cell tumors.

Call-Exner bodies
Mikael Häggström and Nephron, CC BY-SA 3.0 , via Wikimedia Commons
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