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Medicine Review MCQs-III

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All of the following Drugs Cause Nephrogenic Diabetes insipidus EXCEPT?

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Nephrogenic DI occurs due to tubular unresponsiveness to the action of ADH. Can be inherited in an X-linked pattern Medications causing Nephrogenic DI- lithium, foscarnet, and demeclocycline

Demeclocyclin is used for treatment of -

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Demeclocycline has been used in treatment of the syndrome of inappropriate antidiuretic hormone (ADH) secretion (SIADH), as it acts on collecting tubule cells to diminish their responsiveness to ADH, inducing nephrogenic diabetes insipidus.

Diabetes insipidus is defined as the passage of Large Urine volumes of urine with osmolality

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Diabetes insipidus is defined as the passage of Urine volumes (>3 L/24 hr) of urine with osmolality(< 300 mOsm/kg).

Miller moses test done for-

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Miller-Moses test -
Water deprivation (Miller-Moses) test to ensure adequate dehydration and maximal stimulation of ADH for diagnosis of Diabetes insipidus


Purpose of the test:
To measure how much urine is made and how concentrated it becomes when no water is given to a patient for a certain amount of time

Cerebral salt wasting occurs more frequently in which condition?

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Aneurysmal subarachnoid hemorrhage

In hypernatremia the goal is to decrease the serum sodium by not more than -------- meq/L in 24 hours

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Hypernatremia - The goal is to decrease the serum sodium by not more than 10 to 12 meq/L in 24 hours,


What is the maximum rate at which plasma osmolality can be corrected?
2 mOsm/kg/h.
What is the maximum rate at which sodium concentration can be corrected safely?
1 mEq/L/h
Acute hyponatremia should be treated without delay and rapidly at a rate of at least 1 mmol/L/hour, to prevent severe neurologic damage or death.

Severe symptoms are usually due to acute elevation of the plasma sodium concentration to above -

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Severe symptoms are usually due to acute elevation of the plasma sodium concentration to above 157 mmol/L.
Values above 180 mmol/L are associated with a high mortality rate, particularly in adults.

what is the daily protein requirement for an adult?

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1 g/kg per 24 hours

How many kcal in 1 g of carbohydrate?

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4 kcal

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