Medicine MCQs – Immunology

In the process of binding of IgE to human mast cells and basophils which of the following is mainly responsible?

Correct! Wrong!

The α chain is responsible for IgE binding, and the β and γ chains provide for signal transduction

Which is the major prostaglandin produced by mast cells?

Correct! Wrong!

Prostaglandin D2

Which is the primary mediator of vasodilation in "niacin flush"?

Correct! Wrong!

Primary mediator of vasodilation in "niacin flush" - Prostaglandin D2

Which is the least common Immunoglobulin?

Correct! Wrong!

IgE:


IgE is the least prevalent one, with a serum concentration 10,000 times lower than IgG.

Which is the most common Immunoglobulin?

Correct! Wrong!

IgG

Which is the largest immunoglobulin?

Correct! Wrong!

IgM is the largest antibody and the first one to be synthesized in response to an antigen or microbe, accounting for 5% of all immunoglobulins present in the blood. IgM typically exists as polymers of identical subunits, with a pentameric form as the prevalent one.

Binding of IgE to human Mast cells and Basophils is called as -

Correct! Wrong!

Binding of IgE to human mast cells and basophils - Called sensitization
Sensitization - Prepares these cells for subsequent antigen specific activation.

Which immunoglobulin is an important part of the immune response against infection by certain parasitic worms?

Correct! Wrong!

IgE

Prostanoids includes Prostaglandins and ---------

Correct! Wrong!

Prostaglandins and thromboxane A2 (TXA2), collectively termed prostanoids

Which is the smallest immunoglobulin?

Correct! Wrong!

IgG

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