Ankylosing Spondylitis
Contents
- 1 Most common features of Ankylosing Spondylitis
- 2 Most common extraarticular manifestations of Ankylosing Spondylitis
- 3 Human leukocyte antigen associated with Ankylosing Spondylitis
- 4 All of the following are associated with HLA B27 Except
- 5 Inflammatory back pain typically exhibits all Except
- 6 Bamboo spine typically involves
- 7 “sausage digits”
- 8 Extraarticular manifestations
- 9 Inflammatory back pain
- 10 Plain radiographic changes characteristic of AS-
- 11 Early sign
- 12 Squaring” of the vertebral bodies
- 13 Romanus lesions
- 14 Shiny corner sign
- 15 Late sign
- 16 Dagger sign
- 17 Bamboo spine sign
Most common features of Ankylosing Spondylitis
A. Postural abnormalities
B. Buttock pain
C. Hip pain
D. Progressive spinal stiffness
Most common extraarticular manifestations of Ankylosing Spondylitis
A. Aortic Regurgitation
B. Inflammatory bowel disease
C. Acute anterior uveitis
D. Psoriasis
Human leukocyte antigen associated with Ankylosing Spondylitis
A. HLA-DR2
B. HLA-B27
C. HLA-DR4
D. HLA-B47
All of the following are associated with HLA B27 Except
A. Ankylosing spondylitis
B. Reactive arthritis
C. Acute anterior uveitis
D. 21-hydroxylase deficiency
Inflammatory back pain typically exhibits all Except
A. Age of onset less than 40 years
B. Insidious onset
C. Improvement with exercise
D. Improvement with rest
Bamboo spine typically involves
A. Cervical
B. Upper Thoracic
C. Mid Thoracic
D. Thoracolumber
“sausage digits”
Common causes of sausage digit are
- Psoriatic arthropathy
- Osteomyelitis
- Sickle cell disease
- Sarcoidosis
- Tuberculous dactylitis (spina ventosa)
- Leukemia
- Syphilitic dactylitis
- Gout
- Ankylosing spondylitis
Extraarticular manifestations
Most common extraarticular manifestations of AS include
- inflammatory bowel disease (up to 50%),
- acute anterior uveitis (25% to 35%),
- psoriasis (approximately 10%).
Inflammatory back pain
Inflammatory back pain typically exhibits at least four of the five following characteristics:
- Age of onset less than 40 years
- Insidious onset
- Improvement with exercise
- No improvement with rest
- Pain at night with an improvement upon arising
Plain radiographic changes characteristic of AS-
Early sign
Squaring” of the vertebral bodies
Squaring” of the vertebral bodies – best seen on lateral x-ray
Romanus lesions
Shiny corner sign
Shiny corner sign – characterized by small erosions and reactive sclerosis at the corners of the vertebral bodies.
Late sign
Dagger sign
Dagger sign – represented as a single radio dense line running vertically down the spine on frontal radiographs.
Bamboo spine sign
Bamboo spine sign -vertebral body fusion by syndesmophytes
