Urodilatin - Medicine Question Bank

Contents

1 Which of the following is a natriuretic peptide?
2 ALL are TRUE about Urodilatin EXCEPT
3 Urodilatin is an isoform of
4 Urodilatin is a natriuretic peptide which is produced in
5 Which is a synthetic form of urodilatin

Which of the following is a natriuretic peptide?

A. Sacubitril

B. Urotensin II

C. Urodilatin

D. Neprilysin

ANSWER

C. Urodilatin.

– Urodilatin is a hormone.
– Causes natriuresis by increasing renal blood flow.
– It is secreted in response to increased mean arterial pressure and increased blood volume.
– Secreted from the cells of the distal tubule and collecting duct.

ALL are TRUE about Urodilatin EXCEPT

A. Causes natriuresis

B. Secreted in response to decreased mean arterial pressure

C. Lowers serum creatinine

D. Increases urine output

ANSWER

B. Secreted in response to decreased mean arterial pressure.

– It is secreted in response to increased mean arterial pressure and increased blood volume.

Urodilatin is an isoform of

A. ANP

B. BNP

C. CNP

D. DNP

ANSWER

A. ANP

Urodilatin is a natriuretic peptide which is produced in

A. Proximal renal tubules

B. Distal renal tubules

C. Bowman’s capsule

D. Juxtaglomerular cells

ANSWER

B. Distal renal tubules

Which is a synthetic form of urodilatin

A. nesiritide

B. serelaxin

C. ularitide

D. rolofylline

ANSWER

C. ularitide.

Ularitide is a synthetic form of urodilatin.
Ularitide binds to natriuretic peptide receptors located on medullary collecting duct cells and vascular smooth muscle cells, which leads to increased diuresis, natriuresis, and arterial and venous vasodilation.
Clinically, ularitide has been shown to induce natriuresis and, at the same time, decrease plasma concentrations of renin, aldosterone, and angiotensin II, contrary to findings with conventional diuretics.

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Which of the following is a natriuretic peptide?

ALL are TRUE about Urodilatin EXCEPT

Urodilatin is an isoform of

Urodilatin is a natriuretic peptide which is produced in

Which is a synthetic form of urodilatin

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