Dutcher body

Dutcher body

  1. inclusion body structure seen in the nucleus
  2. highly specific to neoplastic myeloma cells
  3. Presence of Dutcher body indicates neoplastic characteristics
  4. Dutcher bodies – invaginate into or overlie the nucleus (intranuclear pseudo inclusions)
  5. Russell bodies – clearly seen to be within the cytoplasm.

Russel bodies – are sometimes found in reactive plasma cells,therefore, their presence is not definitive for neoplasticity

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