Locked-in syndrome


Locked-in syndrome also known as –


A. Coma

B. Pseudocoma

C. Persistent vegetative state

D. Akinetic mutism



Locked-in syndrome is usually characterized by


A. Quadriplegia

B. Hemiplegia

C. Crossed Hemiplegia

D. Monoplegia



All of the following are TRUE about locked-in syndrome EXCEPT –


A. patients is alert

B. quadriplegic

C. cranial nerves are not involved

D. voluntarily able only to move their eyes vertically


All of the following tracts are commonly involved in locked-in syndrome EXCEPT-


A. Flechsig tract

B. Corticospinal tract

C. Corticopontine tract

D. Corticobulbar tract



All of the following are TRUE about locked-in syndrome EXCEPT –


A. Alert

B. Loss of cognitive function

C. Moving their eyes

D. Inability to speak



ALL are TRUE about persistent vegetative state EXCEPT –


A. Loss of cognitive function

B. Lack of awareness

C. Loss of sleep/ wake cycle

D. No blink to visual threat



What is the common involvement in persistent vegetative state –


A. Upper portions of the brain are damaged

B. Lower portions of the brain are damaged

C. Cerebellum is damaged

D. Medulla is damaged



In Locked-in syndrome most common site of lesion is –

A. Anterior pons

B. Posterior pons

C. Anterior Medulla

D. Posterior Medulla



Most common cause of Locked-in syndrome –


A. Vascular

B. Trauma

C. Infection

D. Demyelination



What is the commonest cause of Locked-in syndrome among the following demyelinating diseases?


A. Multiple Sclerosis

B. Central pontine myelinolysis

C. Guillain-Barre syndrome

D. Amyotrophic lateral sclerosis



Which of the following site lesion cause complete locked-in syndrome?


A. Ventral pons

B. Dorsal pons

C. Ventromedial midbrain

D. Medulla



Which of the following artery involvement likely to cause signs of locked-in syndrome?


A. Anterior Cerebral Artery

B. Middle Cerebral Artery

C. Posterior communicating Artery

D. Basilar artery



Extra-Points


What is Flechsig tract ?


Dorsal spinocerebellar tract


  1. Also known as the posterior spinocerebellar tract or Flechsig tract,
  2. It is a somatosensory part of the sensory nervous system that relays unconscious proprioceptive information from the lower limbs and trunk of the body to the cerebellum

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