Na, K-ATPase conformational change where E1 becomes E2 is associated with phosphorylation of ——– residue of E1
Na, K-ATPase – E1 and E2
- Forms of Sodium Pump – Na+-K+ ATPase exists in two forms: E1 and E2.
- Phosphorylation of aspartate residue of E1 with the help of ATP and Mg++ results in conformational change and E1 becomes E2
- Dephosphorylation changes the conformation of E2 to E1