Nephrology MCQs-5

Lost podocytes in the adult are replaced in

A. 90 days

B. 6 months

C. 12 months

D. Cannot be replaced

Adhesive apparatus of podocytes

A. Desmosomes

B. Gap junctions

C. Connexins

D. Foot processes

In the most common inherited form [X-linked form] of nephrogenic diabetes insipidus ——- receptor is defective

A. V1a

B. V1b

C. V2

D. Aquaporin 2

Tamm-Horsfall glycoprotein known as

A. Uromodulin

B. Bence Jones protein

C. Urochrome

D. Calmodulin

Which is the most abundant protein excreted in ordinary urine

A. Calmodulin

B. Bence Jones protein

C. Albumin

D. Uromodulin

Tamm-Horsfall glycoprotein[uromodulin] is secreted by the cells of the

A. Proximal convoluted tube

B. Thick ascending limb of Henle loop

C. Distal convoluted tube

D. Collecting duct

In short

Uromodulin (UMOD) also known as – Tamm–Horsfall protein

Human UMOD gene is located on – chromosome 16

Uromodulin produced by – thick ascending limb of the loop of Henle

Uromodulin represents the most abundant protein in normal human urine

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