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Medicine Question Bank

Which of the following is a Melanocyte derived Giant cell -

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Starburst giant cells are multi-nucleated melanocytes with a stellate appearance due to its prominent dendritic processes. These are useful indicator for the diagnosis of lentigo maligna from photo-damaged skin


Lentigo maligna is a subtype of melanoma in situ that is characterized by an atypical proliferation of melanocytes within the basal epidermis; lentigo maligna that invades the dermis is termed lentigo maligna melanoma

Warthin–Finkeldey cell is a type of giant cell found in -

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Warthin–Finkeldey giant cell found in
- Hyperplastic lymph nodes early in the course of measles
- HIV-infected individuals,
- Kimura disease,
- Rarely in neoplastic (e.g. lymphoma) and non-neoplastic lymph node disorders

Tzanck giant cells seen in all of the following EXCEPT -

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Tzanck giant cells
Multi-nucleated giant cell with molding of the nuclei as they are crowded together.
These are epidermal cells that are much larger than the normal epidermal cells.

What is the order of Giant cells -
Langhans’ Giant Cells , Foreign body giant cells, Touton Giant Cell

Medicine Question Bank 1, 2, 3
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Which organism associated with rat-bite fever?

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Spirillum minus is an organism associated with rat-bite fever .
It stains gram-negative and has a coiled rod shape.

“Henderson-Patterson’s bodies” seen in -

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Henderson-Paterson bodies, can measure 35µm in diameter. Ultrastructural studies have shown that these bodies are membrane-bound sacs that contain numerous molluscum contagiosum virions

In which of the following Cytological Examination shows -Cigar-shaped spindle cells?

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Kaposi’s sarcoma
Kaposi’s sarcoma is caused by a combination of immune suppression (such as due to HIV/AIDS) and infection by Human herpesvirus 8 (HHV8 - also called KS-associated herpesvirus (KSHV)

Koilocyte is a type of squamous epithelial cell seen after viral infection with -

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koilocyte is a squamous epithelial cell that has undergone a number of structural changes
koilocyte is found due to infection of the cell by human papillomavirus (HPV).

Leishman-Donovan bodies seen in cytological examination of -

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L. donovani is the causative agent of visceral leishmaniasis, known as kala-azar ("black fever", particularly in India)

What is the causative organism of cat-scratch disease?

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Spirillum minus - an organism associated with rat-bite fever
Bartonella henselae - causative organism in cat-scratch disease

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Medicine Question Bank
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