Sarcoma of the uterus


Most common sarcoma in the uterus is


A. Leiomyosarcoma
B. Endometrial stromal sarcoma
C. Adenosarcoma
D. Fibrosarcoma



Not true of uterine sarcoma


A. Associated with a poor prognosis than endometrial carcinoma
B. Incidence of uterine sarcoma is 3%–7%
C. More in African women
D. Young women are more affected



Not a variety of uterine sarcoma


A. Leiomyosarcomas
B. Endometrial stromal sarcomas
C. Malignant mixed müllerian tumor
D. Adenosarcoma



Most benign of all the sarcoma uterus is


A. BLeiomyosarcomas
B. Endometrial stromal sarcomas
C. Rhabdomyosarcoma
D. Adenosarcoma



Histologically which sarcoma resembles phylloid tumor of breast


A. Leiomyosarcomas
B. Endometrial stromal sarcomas
C. Rhabdomyosarcoma
D. Adenosarcoma



Which of the following sarcoma is positive for androgen receptor


A. Leiomyosarcomas
B. Endometrial stromal sarcomas
C. Rhabdomyosarcoma
D. Adenosarcoma



Not true of uterine sarcoma


A. Tumors with more than 10 mitotic figures/10 high-power fields have poor prognosis.
B. Intravenous leiomyomatosis has excellent prognosis
C. Commonest histological type is round cell sarcoma
D. Mucosal form of sarcoma can be revealed in diagnostic uterine curettage



In short


  • Blood borne metastasis is the commonest mode of spread. The organs involved are liver, lungs, kidneys, brain, bones.
  • Sarcoma in fibroid has got a better prognosis.
  • Single-agent doxorubicin is standard first-line chemotherapy for uterine leiomyosarcoma (ULMS). 
  • A diagnosis of smooth muscle tumor of uncertain malignant potential (STUMP) is made when morphologically there are equivocal changes. ER and PR may help differentiate between ULMS and STUMP and leiomyoma.

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