Nephrology MCQs-3
Contents
- 1 Most common primary inherited aminoaciduria-
- 2 Most common cause of autosomal recessive proximal renal tubular acidosis
- 3 Most common cause of acquired nephrogenic diabetes insipidus
- 4 Most common causes of pseudohyponatremia
- 5 Most frequent electrolyte disorders
- 6 Hyperphosphatemia is seen in
- 7 Hypokalemia seen in
- 8 In-shorts
- 9 What is the mechanism of Lithium induced nephrogenic diabetes insipidus?
- 10 Long-term lithium use can damage the cells of the kidneys so they no longer respond to AVP.
- 11 Most common cause of nephrogenic diabetes insipidus is-
- 12 What is Pseudohyponatremia?
Most common primary inherited aminoaciduria-
A. Cystinuria
B. Lysinuric protein intolerance
C. Hyperdibasic aminoaciduria
D. Isolated lysinuria
Most common cause of autosomal recessive proximal renal tubular acidosis
A. Amyloidosis
B. Defects in NBCe1-A
C. Lowe syndrome
D. Immaturity of NHE-3
Most common cause of acquired nephrogenic diabetes insipidus
A. Lithium
B. Hypercalcaemia
C. Hypokalemia
D. Pyelonephritis
Most common causes of pseudohyponatremia
A. Light chain disease
B. Myelodysplastic syndromes
C. Hyperlipidemia
D. Heavy chain disease
Most frequent electrolyte disorders
A. Hypokalemia
B. Hypochloremia
C. Hypernatremia
D. Hyponatremia
Hyperphosphatemia is seen in
A. Vitamin D deficiency
B. Chronic kidney disease
C. Hyperparathyroidism
D. Refeeding syndrome
Hypokalemia seen in
A. Insulin deficiency
B. Metabolic acidosis
C. Hyperaldosteronism
D. Acute kidney disease
In-shorts
What is the mechanism of Lithium induced nephrogenic diabetes insipidus?
Long-term lithium use can damage the cells of the kidneys so they no longer respond to AVP.
Lithium – interfere with the production of cAMP
Produces a dramatic reduction AQP2 levels in kidney
Most common cause of nephrogenic diabetes insipidus is-
Bipolar patients treated with lithium, which results in nephrogenic diabetes insipidus in approximately 20% of treated patients
Congenital nephrogenic diabetes insipidus are very rare
Hereditary cause -Genes involved AVPR2 and AQP2
What is Pseudohyponatremia?
Pseudohyponatremia is defined by a serum sodium concentration of less than 135 mEq/L in the setting of a normal serum osmolality (280 to 300 mOsm/kg).
