CRAB criteria

CRAB criteria is used for –

A. Chronic Myeloid Leukemia

B. Multiple Myeloma

C.Renal Cell Carcinoma

D. Papillary Carcinoma of Thyroid

CRAB criteria encompass the most common signs of multiple myeloma:

1. Calcium: serum calcium >0.25 mmol/L (>1 mg/dL) higher than the upper limit of normal or >2.75 mmol/L (>11 mg/dL)
   
2. Renal insufficiency: creatinine clearance <40 mL per minute or serum creatinine >1.77 mol/L (>2 mg/dL)
   
3. Anemia: hemoglobin value of >2g/dL below the lowest limit of normal, or a hemoglobin value <10g/dL
   
4. Bone lesions: osteolytic lesions on skeletal radiography, CT, or PET/CT