Brushfield spots
Contents
Brushfield spots seen in
[A] Marfan syndrome
[B] Down syndrome
[C] Turnor syndrome
[D] Patau syndrome
Brushfield spots located in
[A] Skin
[B] Oral Mucosa
[C] Iris
[D] Upper Chest
Brushfield spots are formed due to aggregation of
[A] Pigments
[B] Hydroxyapatite
[C] Calcium
[D] Connective tissue
Krückmann-Wolfflin bodies
Similar spots like Brushfield spots described by Krückmann and Wolfflin found in individuals without Down syndrome.
Krückmann-Wolfflin bodies compared to Brushfield spots of trisomy 21
| Krückmann-Wolfflin bodies | Brushfield spots of trisomy 21 | |
| 1 | Found in individuals without Down syndrome. | Found in individuals with Down syndrome. |
| 2 | less well defined | More well defined |
| 3 | Fewer in number | More in number |
| 4 | More peripherally located in Iris | Peripherally located in Iris |
