Chemotherapy induced vomiting

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Acute onset of nausea and vomiting after administration of chemotherapy usually resolves

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A. < 24 hours

B. < 48 hours

C. 1 week

D 2 week

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	Nausea & Vomiting after chemotherapy	Time period
1	Acute  onset	Within minutes to hours after administration of chemotherapy and resolving within 24 hours
2	Delayed	Occurs 24 hours or later after administration of chemotherapy
3	Anticipatory	occurs before chemotherapy administration
4	Breakthrough/refractory	Nausea and vomiting that occur despite appropriate prophylaxis

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Agents available to treat chemotherapy-induced nausea and vomiting[ CINV ] include –

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1. 5-HT3 receptor antagonists,
2. NK1 receptor antagonists,
3. corticosteroids,
4. dopamine receptor antagonists
5. benzodiazepines, olanzapine
6. cannabinoids.

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