Immunology MCQs

Prostanoids includes Prostaglandins and ---------

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Prostaglandins and thromboxane A2 (TXA2), collectively termed prostanoids

Which is the major prostaglandin produced by mast cells?

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Prostaglandin D2

Which is the smallest immunoglobulin?

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IgG

Which is the largest immunoglobulin?

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IgM is the largest antibody and the first one to be synthesized in response to an antigen or microbe, accounting for 5% of all immunoglobulins present in the blood. IgM typically exists as polymers of identical subunits, with a pentameric form as the prevalent one.

Which immunoglobulin is an important part of the immune response against infection by certain parasitic worms?

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IgE

Binding of IgE to human Mast cells and Basophils is called as -

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Binding of IgE to human mast cells and basophils - Called sensitization
Sensitization - Prepares these cells for subsequent antigen specific activation.

In the process of binding of IgE to human mast cells and basophils which of the following is mainly responsible?

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The α chain is responsible for IgE binding, and the β and γ chains provide for signal transduction

Which is the most common Immunoglobulin?

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IgG

Which is the least common Immunoglobulin?

Correct! Wrong!

IgE:


IgE is the least prevalent one, with a serum concentration 10,000 times lower than IgG.

Which is the primary mediator of vasodilation in "niacin flush"?

Correct! Wrong!

Primary mediator of vasodilation in "niacin flush" - Prostaglandin D2

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