Endometrial Carcinoma

Corpus cancer syndrome includes all except

A. Obesity
B. Hypertension
C. Diabetes
D. Smoking

Fluorescence Imaging for Robotic Endometrial Sentinel lymph node biopsy (FIRES) uses the dye

A. Indocyanine green
B. Rhodamine
C. Acridine orange
D. Nile red

Not a risk for endometrial cancer

A. Polycystic ovarian syndrome (PCOS)
B. Tamoxifen
C. Use of combined oral contraceptives
D. Functioning ovarian tumors

Not true of Lynch syndrome

A. Is an autosomal dominant genetic disorder
B. Associated with carcinomas of the endometrium
C. Caused by germline mutations in the DNA mismatch repair (MMR) genes
D. Polyposis of colon is the highlight of the syndrome

Most common type of cancer endometrium is

A. Papillary serous carcinoma
B. Mucinous adenocarcinoma
C. Squamous cell carcinoma
D. Adenocarcinoma

Papanicolaou smear is positive in endometrial cancer in

A. 10% cases
B. 30% cases
C. 50% cases
D. 70% cases

In short

  • EC is traditionally classified into two major types (I and II). Type I tumors (G1-G2 endometrioid adenocarcinomas) account for about 80% of endometrial carcinomas, have a favorable prognosis and are estrogen-responsive. 
  • Type II tumors account for 10–20% of EC, include high grade endometrioid tumors, and non-endometrioid tumors (serous, clear-cell, mucinous, squamous, transitional cell, mesonephric, carcinosarcoma, and undifferentiated), have a poor prognosis and are not clearly associated with estrogen stimulation.
  • Extrafascial hysterectomy is the preferred treatment for endometrial carcinoma confined to the body. The surgery includes removal of the uterus, tubes and
  • ovaries of both the sides and cuff of vagina.
  • Contraindications of radiotherapy are presence of a pelvic mass, pelvic kidney, pyometra, pelvic abscess, previous laparotomies and/or adhesions with bowel and prior pelvic radiation.

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