Hutchinson’s Triad

Hutchinson’s Triad, commonly associated with congenital syphilis:


โœ… Hutchinson’s Triad Components

  1. ๐Ÿฆท Hutchinson’s Teeth
    • Notched, peg-shaped permanent incisors.
  2. ๐Ÿ‘๏ธ Interstitial Keratitis
    • Inflammation of the cornea causing visual impairment and sensitivity to light (photophobia).
  3. ๐Ÿ‘‚ Sensorineural Deafness
    • Hearing loss due to inner ear damage.

Hutchinson’s Triad – MCQs

1. Hutchinson’s triad is classically associated with which disease?
A) Congenital Syphilis
B) Congenital Rubella
C) Toxoplasmosis
D) Cytomegalovirus Infection
Hutchinson’s triad is a classic sign of late congenital syphilis.

2. Which of the following is NOT part of Hutchinson’s triad?
A) Interstitial keratitis
B) Hutchinson’s teeth
C) Congenital heart defect
D) Sensorineural deafness
Hutchinson’s triad includes interstitial keratitis, Hutchinson’s teeth, and sensorineural deafness, not congenital heart defect.

3. Hutchinson’s teeth are characterized by:
A) Wide spaced molars
B) Notched, peg-shaped permanent incisors
C) Crowded permanent teeth
D) Enamel hyperplasia
Hutchinson’s teeth are notched, peg-shaped permanent incisors, a hallmark of congenital syphilis.

4. Interstitial keratitis in Hutchinsonโ€™s triad primarily affects which part of the eye?
A) Retina
B) Cornea
C) Lens
D) Optic nerve
Interstitial keratitis involves inflammation of the cornea, causing visual impairment and photophobia.

5. The deafness in Hutchinson’s triad is due to:
A) Conductive hearing loss
B) Sensorineural hearing loss
C) Mixed hearing loss
D) Central auditory processing disorder
Sensorineural deafness occurs in Hutchinson’s triad due to damage to the cochlear nerve.

6. Hutchinson’s triad is most commonly diagnosed at which stage of congenital syphilis?
A) Late congenital syphilis
B) Primary congenital syphilis
C) Secondary congenital syphilis
D) Tertiary congenital syphilis
Hutchinson’s triad appears in late congenital syphilis, typically manifesting in early childhood or later.

7. Which organism causes the condition associated with Hutchinson’s triad?
A) Treponema pallidum
B) Rubella virus
C) Toxoplasma gondii
D) Cytomegalovirus
Treponema pallidum is the bacterium responsible for syphilis, including congenital forms.

8. Which of the following is an early sign of congenital syphilis (before Hutchinson’s triad appears)?
A) Snuffles (nasal discharge)
B) Hutchinson’s teeth
C) Sensorineural deafness
D) Interstitial keratitis
Snuffles (persistent nasal discharge) is an early sign of congenital syphilis before the triad develops.

9. The best preventive measure for Hutchinson’s triad is:
A) Early maternal syphilis screening and treatment during pregnancy
B) Vaccination
C) Isolation of infant at birth
D) Use of antiviral therapy
Early screening and treatment of maternal syphilis during pregnancy prevent congenital syphilis and Hutchinson’s triad.

10. Hutchinson’s teeth primarily affect which teeth?
A) Molars
B) Incisors
C) Canines
D) Premolars
Hutchinson’s teeth are peg-shaped, notched permanent incisors.

11. Sensorineural hearing loss in Hutchinson’s triad results from damage to the:
A) Tympanic membrane
B) Middle ear bones
C) Cochlear nerve or inner ear structures
D) External auditory canal
Sensorineural hearing loss is due to cochlear nerve or inner ear structure damage.

12. Interstitial keratitis in Hutchinsonโ€™s triad can lead to:
A) Corneal scarring and visual impairment
B) Retinal detachment
C) Cataract formation
D) Glaucoma
Inflammation of the cornea in interstitial keratitis causes scarring and potential vision loss.

13. The primary mode of transmission of the disease associated with Hutchinson’s triad is:
A) Vertical transmission from mother to fetus
B) Airborne droplets
C) Contaminated food
D) Sexual contact only after birth
Hutchinsonโ€™s triad is a late manifestation of congenital syphilis, transmitted vertically during pregnancy.

14. The teeth abnormality in Hutchinson’s triad is most visible during which stage?
A) Neonatal stage
B) Adulthood
C) When permanent teeth erupt (around age 6-12)
D) In utero
Hutchinson’s teeth become noticeable when permanent incisors erupt between ages 6 and 12 years.

15. Which of the following best describes interstitial keratitis in Hutchinson’s triad?
A) Inflammation of conjunctiva
B) Inflammation of the corneal stroma without primary involvement of epithelium or endothelium
C) Corneal ulceration due to infection
D) Involvement of the retina
Interstitial keratitis is characterized by stromal inflammation without primary epithelial or endothelial involvement.

16. The most important factor in preventing Hutchinson’s triad is:
A) Regular pediatric check-ups
B) Good dental hygiene
C) Prenatal syphilis screening and treatment
D) Childhood vaccinations
Prenatal screening and treatment of syphilis is the most effective way to prevent congenital syphilis and Hutchinsonโ€™s triad.

17. Hutchinson’s triad appears in approximately what percentage of congenital syphilis cases?
A) 90%
B) 50%
C) 5-10%
D) Less than 1%
Hutchinson’s triad occurs in about 5-10% of congenital syphilis cases.

18. Late congenital syphilis is diagnosed at which age?
A) Birth
B) Within the first month
C) After 2 years of age
D) During teenage years
Late congenital syphilis is diagnosed after 2 years of age, when features such as Hutchinsonโ€™s triad become evident.

19. What is the treatment of choice for congenital syphilis associated with Hutchinsonโ€™s triad?
A) Penicillin G
B) Acyclovir
C) Ciprofloxacin
D) Corticosteroids
Penicillin G is the treatment of choice for congenital syphilis, regardless of the disease stage.

20. Hutchinson’s triad is named after which physician?
A) Thomas Sydenham
B) Robert Koch
C) Jonathan Hutchinson
D) William Osler
Jonathan Hutchinson first described the triad in congenital syphilis.

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