Heart Failure -I

What is the commonest cause of heart failure?

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Ischaemic heart disease - 35–40%


Cardiomyopathy (dilated) - 30–34% Hypertension - 15–20%

Weight loss of 4.5 kg in ............ days in response to treatment is a Framingham major criteria.

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The Framingham criteria for the diagnosis of heart failure consists of the concurrent presence of either two major criteria or one major and two minor criteria.
Major criteria comprise the following:
Paroxysmal nocturnal dyspnea
Weight loss of 4.5 kg in 5 days in response to treatment
Neck vein distention
Rales
Acute pulmonary edema
Hepatojugular reflux
S 3 gallop
Central venous pressure greater than 16 cm water
Circulation time of 25 seconds or longer
Radiographic cardiomegaly
Pulmonary edema, visceral congestion, or cardiomegaly at autopsy
Minor criteria (accepted only if they cannot be attributed to another medical condition) are as follows:
Nocturnal cough
Dyspnea on ordinary exertion
A decrease in vital capacity by one third the maximal value recorded
Pleural effusion
Tachycardia (rate of 120 bpm)
Hepatomegaly
Bilateral ankle edema

Licorice can worsen heart failure by -

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Licorice can worsen heart failure by increasing blood pressure and promoting fluid retention.

Yohimbine can exacerbate heart failure by increasing blood pressure through -

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Yohimbine can exacerbate heart failure by increasing blood pressure through alpha-2 adrenergic receptor antagonism

Which of the following stages of heart failure the patient belongs to when the patient has structural heart disorder, but no symptoms at any stage?

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Stage A: People at high risk for developing HF in the future, but no functional or structural heart disorder Stage B: A structural heart disorder, but no symptoms at any stage Stage C: Previous or current symptoms of heart failure in the context of an underlying structural heart problem, but managed with medical treatment Stage D: Advanced disease requiring hospital-based support, a heart transplant, or palliative care

Heart failure cells are -

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Heart failure cells are siderophages generated in the alveoli of the lungs of people with left heart failure or chronic pulmonary edema

Patients who achieve at least............. MET-minutes/week had lower heart failure

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Recommended minimum by U.S. guidelines -
Patients who achieve at least 500 MET-minutes/week had lower heart failure

Which of the following should be used in those patients who still have symptoms while on an ACE-I or ARB, beta blocker, and a mineralocorticoid receptor antagonist?

Correct! Wrong!

Sacubitril/valsartan should be used in those who still have symptoms while on an ACE-I or ARB, beta blocker, and a mineralocorticoid receptor antagonist as it reduces the risks of cardiovascular mortality and hospitalization for heart failure by a further 4.7% (absolute risk reduction).

All of the following is used for risk Stratification in heart failure EXCEPT?

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Framingham criteria for the diagnosis of heart failure

Tolvaptan antagonises which of the following receptor?

Correct! Wrong!

VAPTANS



Unselective (mixed V1A/V2)
Conivaptan
V1A selective (V1RA)
Relcovaptan
V1B selective (V3RA)
Nelivaptan
V2 selective (V2RA)
Lixivaptan
Mozavaptan
Satavaptan
Tolvaptan

Atrial fibrillation occurs in approximately ------------% of patients with heart failure.

Correct! Wrong!

Atrial fibrillation occurs in approximately 20% of patients with heart failure and causes further impairment of cardiac function

Heart Failure -I
Heart Failure -I
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