Granulosa cell tumors

Granulosa cell tumors

1. Call–Exner bodies
2. “coffee-bean” nuclei
3. estrogen secreting tumors
4. Biomarker for granulosa cell tumours – Inhibin [hormone]

Call–Exner bodies

1. gives a follicle-like appearance
2. small eosinophilic fluid-filled punched out spaces between granulosa cells.
3. They are pathognomonic for granulosa cell tumors.

Mikael Häggström and Nephron, CC BY-SA 3.0 , via Wikimedia Commons

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