Ghost cells


Ghost cells generally lack nuclear and cytoplasmic details and are characteristically seen in All of the following EXCEPT

[A] Calcifying cystic odontogenic tumor
[B] Craniopharyngiomas
[C] Giant cell tumor
[D] Pilomatricomas



What is a ‘Ghost cell’?



▪️There is cell death with retainment of cellular architecture
▪️Ghost cells indicate coagulative necrosis
▪️They are dead cells


They are found in:


▪️Craniopharyngioma (Rathke pouch)
▪️Odontoma
▪️Ameloblastic fibroma
▪️Calcifying odontogenic cyst (Gorlin cyst)
▪️Pilomatricoma


Infarcted Lymph Node – Ghost cells


  • Usually result of involvement by lymphoma
  • Vascular occlusion may explain necrosis
  • Outlines of necrotic lymphoma cells (“ghost cells”)

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