Delirium

Delirium

Hallmark of delirium is a defcit of


[A] Attention
[B] Memory
[C] Visuospatial tasks [D] Language



Hallmark of delirium


Hallmark of delirium is a deficit of attention, although all cognitive domainsโ€”including memory,
executive unction, visuospatial tasks, and languageโ€” are variably involved.


Associated symptoms that may be present in some cases include altered sleep-wake cycles, perceptual disturbances such as hallucinations or delusions, a ect changes, and autonomic ndings that include heart rate and blood pressure instability.


primary hallmark of delirium is an acute, fluctuating disturbance in attention and awareness. This involves a reduced ability to direct, focus, sustain, or shift attention, often developing rapidly over hours to days. 

Key Clinical Features

Medical professionals often look for four core features to diagnose delirium, notably used in the Confusion Assessment Method (CAM)

  • Acute Onset and Fluctuating Course: Symptoms appear suddenly and often change in severity throughout the day, sometimes worsening at nightโ€”a phenomenon known as “sundowning”.
  • Inattention: The person may be easily distracted or have significant trouble following a conversation or command.
  • Disorganised Thinking: This manifests as incoherent, rambling, or nonsensical speech.
  • Altered Level of Consciousness: This can range from hyperalertness and agitation to extreme drowsiness and lethargy. 

Common Subtypes

Delirium is often categorized based on the patient’s activity level: 

  • Hyperactive: Characterized by restlessness, agitation, and sometimes hallucinations or delusions. It is often the easiest type to recognize.
  • Hypoactive: The most common but frequently missed type, characterized by sluggishness, drowsiness, and withdrawal. It is often misidentified as depression.
  • Mixed: Involves symptoms that fluctuate between the hyperactive and hypoactive states.

Distinguishing from Dementia

While both conditions involve confusion, they have distinct profiles:

Feature DeliriumDementia
OnsetSudden/Acute (hours to days)Slow/Insidious (months to years)
AttentionSignificantly impaired early onGenerally preserved until late stages
CourseFluctuating (better/worse during the day)Steady and progressive
ReversibilityUsually reversible if cause is treatedNearly always irreversible

1. Hallmark feature of delirium:
A. Inattention
B. Memory loss
C. Aphasia
D. Apraxia
Inattention is the defining feature.

2. Most common cause in elderly:
A. Stroke
B. Infection
C. Tumor
D. Trauma
UTI and pneumonia are most common triggers.

3. Neurotransmitter decreased:
A. Acetylcholine
B. Dopamine
C. Serotonin
D. GABA
Cholinergic deficiency is key.

4. Common hallucination:
A. Auditory
B. Visual
C. Olfactory
D. Gustatory
Visual hallucinations predominate.

5. Course:
A. Progressive
B. Fluctuating
C. Static
D. Chronic
Fluctuation is hallmark.

6. Best bedside tool:
A. CAM
B. MMSE
C. GCS
D. NIHSS
CAM is gold standard bedside.

7. Hypoactive delirium:
A. Often missed
B. Obvious
C. Rare
D. Severe only
Leads to underdiagnosis.

8. Drug of choice:
A. Diazepam
B. Haloperidol
C. Lithium
D. Fluoxetine
Haloperidol is first-line.

9. Benzodiazepines indicated in:
A. Alcohol withdrawal
B. All delirium
C. Infection
D. Dementia
Use only in withdrawal states.

10. Key differentiator:
A. Acute onset
B. Memory
C. Age
D. Behavior
Delirium is acute.

11. Sundowning:
A. Evening worsening
B. Morning confusion
C. Sleep apnea
D. Coma
Symptoms worsen at night.

12. Reversible cause:
A. Drugs
B. Alzheimer
C. Stroke
D. Tumor
Drug-induced delirium is common.

13. Attention test:
A. Digit span
B. Naming
C. Writing
D. Drawing
Digit span checks attention.

14. EEG finding:
A. Slowing
B. Spikes
C. Normal
D. Alpha
Diffuse slowing seen.

15. Most important step:
A. Treat cause
B. Sedate
C. MRI
D. Restrain
Always treat underlying cause.

16. Duration:
A. Daysโ€“weeks
B. Years
C. Lifetime
D. Minutes
Usually reversible.

17. Risk factor:
A. Old age
B. Youth
C. Fitness
D. Diet
Elderly high risk.

18. Consciousness:
A. Altered
B. Normal
C. High
D. Fixed
Altered consciousness is core.

19. Nature:
A. Emergency
B. Benign
C. Chronic
D. Psychiatric only
Always urgent evaluation needed.

20. Diagnostic triad:
A. Acute + inattention + fluctuating
B. Memory + aphasia
C. Tremor + rigidity
D. Seizure + coma
CAM-based criteria.

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