Medicine Review
Bronchoscopy: may demonstrate a ‘cobblestone’ appearance of the mucosa.
Bronchial and transbronchial biopsies usually show non-caseating granulomas.
HRCT: characteristic appearances include reticulonodular opacities that follow a perilymphatic distribution
Pulmonary Function Impairment
Renal Impairment.
Unexplained Dyspnea,
Restrictive Pattern On Pulmonary Function Tests
Elevated Hemidiaphragm.
Systemic Sclerosis,
Sjogren's Syndrome,
Rheumatoid Arthritis
para-aminosalicylic acid (PAS),
sulfasalazine,
imipramine,
chlorpropamide,
phenylbutazone
More Common In Men
Almost Exclusively In Smokers
Pathology - Glomerulonephritis and Pulmonary Haemorrhage.
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Pulmonary Infiltrates, Hypoxia and Haemoptysis
Commonly Precede Renal Involvement.
Miosis -constricted pupil
Partial ptosis,
Anhidrosis -Loss of hemifacial sweating
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Enophthalmos- sinking of the eyeball into the bony cavity that protects the eye.