Neurology Notes : Wilbrand’s knee
Contents
- 1 Wilbrand’s knee:
- 2 Most commonly associated tumor associated with – Rapidly progressive bilateral visual loss caused by paraneoplastic processes
- 3 Most common inherited optic neuropathy is
- 4 Most common causes of unilateral optic disc edema –
- 5 Most common carcinoma metastasize to the optic nerve
- 6 Antibody most commonly identified and directed toward –
- 7 Which infectious disorder most commonly associated with significant papilledema?
- 8 Which Vitamin is associated with risk of Pseudotumor cerebri?
- 9 Optic Disc Drusen
- 10 Most common causes of unilateral retrobulbar optic neuropathy –
- 11 Lhermitte sign
- 12 Most common cause of inherited chorea –
- 13 Asterixis – Liver Flap is Example of ————— myoclonus.
Wilbrand’s knee:
Inferonasal fibres of the optic nerve which go into the contralateral optic nerve 4 mm before crossing over to the opposite optic tract.
A lesion here produces a junctional scotoma in the superior temporal field of the optic nerve opposite the site of injury.
Most commonly associated tumor associated with – Rapidly progressive bilateral visual loss caused by paraneoplastic processes
Small cell carcinoma of lung
Most common inherited optic neuropathy is
Dominant optic atrophy – autosomal dominant
Most common causes of unilateral optic disc edema –
- Nonarteritic anterior ischemic optic neuropathy (NAION)
- Optic neuritis
- Orbital compressive lesions
Most common carcinoma metastasize to the optic nerve
Carcinoma Breast and Lung carcinomas
Antibody most commonly identified and directed toward –
- Paraneoplastic optic neuropathy,- antibodies to collapsin response mediator protein 5 (CRMP5).
- Paraneoplastic retinopathies-cancer-associated retinopathy – antibodies to recoverin protein
- Melanoma-associated retinopathy – antibodies to rod ganglion cells
Which infectious disorder most commonly associated with significant papilledema?
Cryptococcal meningitis
Which Vitamin is associated with risk of Pseudotumor cerebri?
Vitamin A
Optic Disc Drusen
Optic disc drusen- common cause of pseudopapilledema,
Due to calcium deposits within the optic nerve head.
Most common causes of unilateral retrobulbar optic neuropathy –
Optic neuritis and compressive lesions.
Lhermitte sign
Electric shock-like sensations radiating down the spine, which may be transmitted into the extremities. Occur with neck flexion
This phenomenon may occur with lesions of the posterior columns, most commonly from MS
Most common cause of inherited chorea –
Huntington disease
Asterixis – Liver Flap is Example of ————— myoclonus.
Negative myoclonus
