Vulval Carcinoma

Not true of vulval carcinoma is –

A. More common in postmenopausal women with a median age of 60.
B. Common amongst Afro-asians
C. Greater association with nulliparity
D. Human papillomavirus (HPV) DNA is found

All are risk factors for vulval carcinoma except

A. Lichen planus
B. HPV type 32
C. Lymphogranuloma venereum
D. Poor hygiene

Most common histologic type of vulval carcinoma –

A. Squamous cell carcinoma
B. Melanoma
C. Sarcoma
D. Basalioma

Percentage of women suffering from VIN III proceed to invasive vulvar cancer-

A. 30%
B. 80%
C. 50%
D. 16%

Not true of vulvar non-neoplastic epithelial disorders (VNED) leading to cancer

A. Common in elderly women
B. Low rate of HPV infections
C. Lichen sclerosus is a risk factor
D. Often seen with sexually transmitted diseases (STD)

The commonest site of lesion in Vulvar melanoma –

A. Anterior two-third of labia majora
B. Clitoris
C. Vestibule
D. Vaginal introitus

Frequency of contralateral metastases in vulvar cancer is

A. 10%
B. 13%
C. 19%
D. 25%


The risk of nodal metastasis increases with the stage of disease, the size of lesion, and the depth of invasion. These are the most important prognostic factors for vulvar cancer.

MRI may play a role in evaluation of the local extent of disease in advanced cases, especially if urethral invasion is suspected

Radical vulvectomy implies removal of the entire vulva down to the level of the deep fascia of the thigh, the periosteum of the pubis, and the inferior fascia of the urogenital diaphragm. A tumor-free margin ≥1 cm is required since a smaller margin is associated with an increased local recurrence risk.

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