Renin
Contents
- 1 Angiotensinogen is cleaved to form angiotensin I by
- 2 Renin is secreted in response to all of the following EXCEPT –
- 3 Renin cleave angiotensinogen to form angiotensin I by using which of the following activity?
- 4 What is the primary function of Renin ?
- 5 What is the action of Candesartan?
- 6 Aliskiren is classified as –
- 7 Which of the following is correct?
- 8 In shorts
- 9 Renin Inhibitor – Mechanism of Action
Angiotensinogen is cleaved to form angiotensin I by
A. Renin
B. Angiotensin Converting Enzyme
C. Hydrolase
D. Aminotransferases
Renin is secreted in response to all of the following EXCEPT –
A. Decrease in arterial blood pressure
B. Decrease in blood volume
C. Increase in sodium load delivered to the distal tubule
D. Stimulation of β1 adrenergic receptors.
Renin cleave angiotensinogen to form angiotensin I by using which of the following activity?
A. Endopeptidase
B. Carboxypeptidase
C. Aminopeptidase
D. Prolinase
What is the primary function of Renin ?
A. Increase water retention
B. Increase in blood pressure
C. Stimulate Distal convoluted tubles
D. Reduce the blood pressure
What is the action of Candesartan?
A. ACE inhibitor
B. Renin inhibitor
C. Angiotensin II receptor blocker
D. Aminopeptidase
Aliskiren is classified as –
A. ACE inhibitor
B. Renin inhibitor
C. Angiotensin II receptor blocker
D. Aminopeptidase
Which of the following is correct?
A. Not effective in lowering blood pressure
B. Aliskiren is used with ARBs or ACE inhibitors in patients with GFR < 60 mL/min
C. Angiotensin II receptor antagonist
D. Pepstatin – the first renin inhibitor
In shorts
- Renin secretion is also stimulated by sympathetic nervous stimulation, mainly through β1 adrenoreceptor activation
- Aliskiren should not be used with ARBs or ACE inhibitors in patients with moderate to severe renal impairment – where glomerular filtration rate [GFR] < 60 mL/min
- Pepstatin – the first renin inhibitor
Renin Inhibitor – Mechanism of Action
