Factors affecting Wound Healing

Which are the main cells of wound healing?

A. Neutrophils

B. Macrophages

C. B Lymphocytes

D. T-Cells

The basic structural unit of collagen fibrils

A. Tropomycin

B. Nidogen

C. Tropocollagen

D. Alpha helix

Smallest amino acid is

A. Lysine

B. Valine

C. Glycine

D. Proline

Fibroblast requires which vitamin to produce collagen?

A vitamin B6

B. vitamin C

C. vitamin D

D. vitamin E

Haemoglobin less than ————- causes poor oxygenation of tissues preventing healing of the wounds.

A. 8g %

B. 9g %

C. 10g %

D. 11g %

β-haemolytic streptococci more than ———- of tissue prevent wounds healing.

A. 102 per gram

B. 103 per gram

C. 105 per gram

D. 107 per gram


Arginine is the immediate precursor of nitric oxide


Copper is a required co-factor for cytochrome oxidase, for cytosolic anti-oxidant superoxide dismutase, and for the optimal cross-linking of collagen


Iron is required for the hydroxylation of proline and lysine

Serum albumin level

Serum albumin level less than 2 g/dl causes prolonged inflammatory phase,
decreased fibroplasia, neovascularisation and cell synthesis and wound remodeling and hence decreased wound healing.


Collagen is the major protein component of connective tissue; it contains mainly glycine, proline, and hydroxyproline.

vitamin C

Collagen synthesis requires hydroxylation of lysine and proline, and co-factors such as ferrous
iron and vitamin C.

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