Factors affecting Wound Healing


Which are the main cells of wound healing?


A. Neutrophils

B. Macrophages

C. B Lymphocytes

D. T-Cells



The basic structural unit of collagen fibrils


A. Tropomycin

B. Nidogen

C. Tropocollagen

D. Alpha helix



Smallest amino acid is


A. Lysine

B. Valine

C. Glycine

D. Proline



Fibroblast requires which vitamin to produce collagen?


A vitamin B6

B. vitamin C

C. vitamin D

D. vitamin E



Haemoglobin less than ————- causes poor oxygenation of tissues preventing healing of the wounds.


A. 8g %

B. 9g %

C. 10g %

D. 11g %



β-haemolytic streptococci more than ———- of tissue prevent wounds healing.


A. 102 per gram

B. 103 per gram

C. 105 per gram

D. 107 per gram



Arginine

Arginine is the immediate precursor of nitric oxide


Copper

Copper is a required co-factor for cytochrome oxidase, for cytosolic anti-oxidant superoxide dismutase, and for the optimal cross-linking of collagen


Iron

Iron is required for the hydroxylation of proline and lysine


Serum albumin level

Serum albumin level less than 2 g/dl causes prolonged inflammatory phase,
decreased fibroplasia, neovascularisation and cell synthesis and wound remodeling and hence decreased wound healing.


Collagen

Collagen is the major protein component of connective tissue; it contains mainly glycine, proline, and hydroxyproline.


vitamin C

Collagen synthesis requires hydroxylation of lysine and proline, and co-factors such as ferrous
iron and vitamin C.


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