Nephrology MCQs-II

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Proteinuria in adults is defined as excessive protein excretion in the urine, generally greater than --------------

Correct! Wrong!

Proteinuria is defined as excessive protein excretion in the urine, generally greater than 150 mg/24 hours in adults

Which of the following cast is not indicative of kidney disease ?

Correct! Wrong!

Hyaline casts - Not indicative of kidney disease
Hyaline casts seen in cases -
- Concentrated urine,
- febrile disease,
- diuretic therapy,
- after strenuous exercise


Red cell casts - Glomerulonephritis
White cell casts - Indicative of infection or inflammation, Pyelonephritis, interstitial nephritis,
Renal tubular cell casts -Acute tubular necrosis, interstitial nephritis
Granular (muddy brown) casts- Nonspecific; can indicate acute tubular necrosis

Bence Jones proteins are missed with dipstick analysis because -

Correct! Wrong!

Evaluation of proteinuria by urine dipstick does not actually measure protein but instead detects the negative electrochemical charge that characterizes albumin.
Bence Jones proteins - positively charged so Bence Jones proteins are missed with dipstick analysis.

Urine dipstick for proteins DIRECTLY detects -

Correct! Wrong!

Evaluation of proteinuria by urine dipstick does not actually measure protein but instead detects the negative electrochemical charge that characterizes albumin.

Urine protein to creatinine ratio (P/C ratio) is a fast and simple method of detecting -

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Urine protein to creatinine ratio (P/C ratio) is an alternative, fast and simple method of detecting and estimating the quantitative assessment of proteinuria.

Bence Jones proteins can be detected by the addition of --------------- to the urine specimen

Correct! Wrong!

Bence Jones proteins can be detected by the addition of sulfosalicylic acid to the urine specimen

Creatinine clearance is approximately -------- mL/min in healthy young men

Correct! Wrong!

Creatinine clearance is approximately 100 mL/min in healthy young women and 120 mL/min in healthy young men

Cockcroft-Gault formula is used to measure -

Correct! Wrong!

Cockcroft-Gault formula: Estimated creatinine clearance rate (eCCR)
Creatinine clearance can be estimated using serum creatinine levels.

Cockcroft-Gault formula uses all of the following EXCEPT -

Correct! Wrong!

The resulting CrCl is multiplied by 0.85 if the patient is female to correct for the lower CrCl in females.

Which is the main predictor for Creatinine clearance in Cockcroft-Gault formula?

Correct! Wrong!

The Cockcroft-Gault formula is dependent on age as its main predictor for Creatinine clearance.

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