Medicine Review -I

Which disease is suggested by the following Findings?
Bronchoscopy: may demonstrate a ‘cobblestone’ appearance of the mucosa.
Bronchial and transbronchial biopsies usually show non-caseating granulomas.
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Sarcoidosis
HRCT: characteristic appearances include reticulonodular opacities that follow a perilymphatic distribution

What are the indications of Systemic corticosteroids in Sarcoidosis?
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Indications of Systemic corticosteroids in Sarcoidosis- Hypercalcaemia,
Pulmonary Function Impairment
Renal Impairment.

Combination of rheumatoid nodules and pneumoconiosis is known as —-
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Caplan’s syndrome

Shrinking lung syndrome (SLS) is a rare complication of which disease?
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Shrinking lung syndrome (SLS) is a rare complication of systemic lupus erythematosus (SLE) characterized by -
Unexplained Dyspnea,
Restrictive Pattern On Pulmonary Function Tests
Elevated Hemidiaphragm.

What are the conditions we can find Shrinking lung syndrome?
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Shrinking lung syndrome occurs most commonly in systemic lupus erythematosus but there are rare reports of it developing in -
Systemic Sclerosis,
Sjogren's Syndrome,
Rheumatoid Arthritis

What are the drugs that can cause Pulmonary eosinophilia?
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Drugs -causing Pulmonary eosinophilia - Nitrofurantoin,
para-aminosalicylic acid (PAS),
sulfasalazine,
imipramine,
chlorpropamide,
phenylbutazone

Goodpasture’s syndrome more common in Men or Women?
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Goodpasture’s syndrome: IgG antibodies bind to the glomerular or alveolar basement membranes
More Common In Men
Almost Exclusively In Smokers
Pathology - Glomerulonephritis and Pulmonary Haemorrhage.
—--------------------------
Pulmonary Infiltrates, Hypoxia and Haemoptysis
Commonly Precede Renal Involvement.

Acute radiation pneumonitis is typically seen within ------------ wks of lung irradiation
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Acute radiation pneumonitis is typically seen within 6–12 wks of lung irradiation

Enlargement of the hilar glands with an ‘egg-shell’ calcification is seen in which condition?
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Enlargement of the hilar glands with an ‘egg-shell’ calcification is uncommon and nonspecific finding in Silicosis.

What are the classic signs of Horner's syndrome?
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Classic triad -
Miosis -constricted pupil
Partial ptosis,
Anhidrosis -Loss of hemifacial sweating
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Enophthalmos- sinking of the eyeball into the bony cavity that protects the eye.

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