Transient myeloproliferative disease


Transient myeloproliferative disease usually develops in


[A] Marfan syndrome
[B] Down syndrome
[C] Turnor syndrome
[D] Patau syndrome



Transient myeloproliferative disease commonly affects


[A] Newborn
[B] After 5 years of age
[C] After 15 years of age
[D] After 25 years of age



Transient myeloproliferative disease is a


[A] Benign condition
[B] Malignancy of bone marrow
[C] Precancerous condition
[D] Hereditary cancer



Which is correct about Transient myeloproliferative disease ?


[A] Benign condition
[B] Always progress to Malignancy
[C] Resolves spontaneously
[D] Usually resolves after treatment



Most common organs involved in transient myeloproliferative disease


[A] Liver
[B] Spleen
[C] G.I.Tract
[D] Kidney



Most common cause of organs damage in transient myeloproliferative disease


[A] Autoimmune mechanism
[B] Hemolysis
[C] Light chain deposite
[D] Megakaryoblast infiltration



Transient myeloproliferative disease


Transient myeloproliferative diseaseCharacteristics
1DiagnosisSeen in Newborn – Diagnosed prenatally or within ~3 months of birth
2Resolution of TMDResolves rapidly and spontaneously in 3 months
3Acute megakaryoblastic leukemia10% of TMD develop acute megakaryoblastic leukemia – during the 5 years following its resolution.
4 Associated with Down syndrome
Transient myeloproliferative disease

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