Reticulocytes
Contents
Reticulocytes all are TRUE EXCEPT
A. Produced in the bone marrow
B. Immature red blood cells
C. Mature into RBCs in 7 days
D. Indicator of erythropoiesis activity
In comparison to a mature RBC reticulocytes have all of the following EXCEPT
A. Immature
B. Greater volume
C. Lower hemoglobin content
D. Lower hemoglobin concentration
Which is corrected reticulocyte count used in anemias?
A. Reticulocyte count
B. Reticulocyte production index
C. Immature reticulocyte fraction
D. Reticulocyte hemoglobin content
Reticulocyte hemoglobin content less than 28 pg is a good predictor for
A. Glucose-6-phosphate dehydrogenase (G6PD) deficiency
B. Hereditary spherocytosis
C. Sickle cell anemia
D. Iron deficiency anemia
In shorts
Flow cytometry is the most typical method of counting reticulocytes
Reticulocytes can only synthesize hemoglobin while in the bone marrow. Thus, once they enter the peripheral blood, they have the maximum hemoglobin content they can have
Increased reticulocyte percentages are seen in hemolytic disorders, whether intrinsic (e.g., hemoglobinopathy or enzymopathy) or extrinsic (e.g., traumatic, heart valve, acquired immune hemolytic anemia).
As long as the hemolytic cause is not corrected, the reticulocyte count will remain elevated.
| Reference ranges for the reticulocyte count | ||
| 1 | Adult/elderly/child | 0.5-2% |
| 2 | Infant | 0.5-3.1% |
| 3 | Newborn | 2.5-6.5% |
