Neurology Review MCQs – I
Hirano bodies are seen in-
Hirano bodies are intracellular aggregates of actin and actin-associated proteins first observed in neurons
Hirano bodies are found in the nerve cells of individuals afflicted with certain neurodegenerative disorders, such as Alzheimer's disease and Creutzfeldt–Jakob disease
Hirano bodies are intracellular aggregates of -
Hirano bodies are intracellular aggregates of actin and actin-associated proteins
Lewy bodies are seen in -
Lewy bodies are the inclusion bodies – abnormal aggregations of protein – that develop inside nerve cells affected by Parkinson's disease
Papp-Lantos inclusions are found in-
The presence of inclusion bodies known as Papp–Lantos bodies, in the movement, balance, and autonomic-control centres of the brain are the defining histopathologic hallmark of Multiple system atrophy.
The major filamentous component of Papp-Lantos bodies- is alpha-synuclein
Bunina bodies are found in?
Bunina bodies are small eosinophilic neuronal cytoplasmic inclusions found in the remaining lower motor neurons (LMNs) of patients with sporadic amyotrophic lateral sclerosis , being a specific feature of the cellular pathology.
Collins bodies are seen in -
Neuroserpin inclusion bodies or Collins bodies
Collins bodies form within nerve cells.
Collins bodies form in cortical and subcortical neurons
Collins bodies disrupt the cells' normal functioning and ultimately lead to cell death
Negri bodies are seen in -
Negri bodies - found in the cytoplasm of nerve cells containing the virus of rabies, especially in pyramidal cells within Ammon's horn of the hippocampus.
Relapsing and remitting symptoms involving different levels of the nervous system suggests which of the following disease ?
TYPES OF MULTIPLE SCLEROSIS
Clinically isolated syndrome Relapsing-remitting MS Primary progressive MS Secondary progressive MS
Which of the following variant is most severe form of Multiple Sclerosis?
Types of Multiple Sclerosis ?
Clinically isolated syndrome
Primary progressive MS
Secondary progressive MS
Male patients with primary progressive MS have the worst prognosis, with less favorable response to treatment and rapidly accumulating disability. The higher incidence of spinal cord lesions in primary progressive MS is also a factor in the rapid development of disability.
Which of the following is also called Marburg acute multiple sclerosis?
Marburg acute multiple sclerosis, also known as Marburg multiple sclerosis or acute fulminant multiple sclerosis
Marburg variant of MS is an acute fulminant demyelinating process which in most cases progresses inexorably to death within 1–2 years