Majocchi granuloma

Majocchi granuloma seen in

Majocchi granuloma seen in

[A] SLE
[B] Sarcoidosis
[C] Infective Endocarditis
[D] Fungal Infection

Most common dermatophyte implicated in Majocchi granuloma

Most common dermatophyte implicated in Majocchi granuloma

[A] Trichophyton mentagrophytes
[B] T. violaceum
[C] Trichophyton rubrum
[D] T. tonsurans

• The most common dermatophyte implicated in Majocchi granuloma is Trichophyton rubrum.
• Other fungi – T. mentagrophytes, T. violaceum, T. tonsurans, Microsporum canis, Epidermophyton floccosum and Aspergillus species can cause Majocchi granuloma.

• Majocchi granuloma – also called nodular granulomatous perifolliculitis or granuloma trichophyticum
• Dermatophytes invade keratinous tissue such as hair, skin and nails.
• Majocchi’s granuloma is an uncommon complication of cutaneous fungal infections in which dermatophytes disseminate into the subcutaneous tissue secondary to skin breakdown, immunosuppression, or topical steroid use resulting in a deep, inflammatory disease.

Majocchi’s granuloma

Majocchi’s granuloma- Clinical manifestation on the patient’s forearm before and after treatment. a Before treatment—Clinical photograph showing a 3 × 3.5 cm lump on her left forearm, with a clear boundary, a few scales and scabs on the surface. b After 2 weeks of treatment with oral itraconazole and moxibustion

Annals of Clinical Microbiology and Antimicrobials