Image Question-55
Contents
What is the Typical Finding in the Image?
Look at the cell with arrow mark.
Findings
- Bi-lobed neutrophil
- Toxic granulation
- Cytoplasmic vacuolization
- Bluish Dohle body
Pelger-Huet Anomoly
This is called – Pelger-Huet Anomoly
Normal neutrophil nucleus is multilobed – 3–5 segments joined by thin strands
Nucleus of neutrophil – unusual shape [bilobed, peanut or dumbbell-shaped]
- Pelger–Huët anomaly is a blood laminopathy associated with the lamin B receptor,
- Neutrophils and Eosinophils – have nuclei with unusual shape [bilobed, peanut or dumbbell-shaped]
- Unusual structure (coarse and lumpy)
