Image Question-51


What is the cell marked in the image?


Collections of large histiocytes with granular eosinophilic cytoplasm: von Hansemann cells. The cytoplasm contains abundant basophilic inclusions with a variable size: Michaelis–Gutmann bodies. Some of them are laminated and others have targetoid appearance (arrows). The typical targetoid appearance may not be apparent if the plane of section does not pass through the dense central core (headarrow). Michaelis–Gutmann bodies demonstrate positive results using periodic acid-Schiff stain, von Kossa stain for calcium and sometimes Perls Prussian blue stain for iron (haematoxylin–eosin, original magnification, × 1000).

What is the cell marked in the image?


A. Langhans giant cell

B. Touton giant cells

C. von Hansemann cells

D. Reed–Sternberg cell



von Hansemann cells contains inclusions called


A. Collins bodies

B. Michaelis–Gutmann bodies

C. Bunina bodies

D. Pappenheimer bodies



All are correct for Michaelis–Gutmann bodies Except


A. Concentrically layered

B. Basophilic inclusions

C. Found in Hansemann cells

D. Found in Spleen



M-G bodies are a pathognomonic feature of


A. Urothelial carcinoma

B. Malakoplakia

C. Renal cell carcinoma

D. Ureterocele



Malakoplakia is a condition associated with


A. Urothelial carcinoma

B. Chronic cystitis

C. Renal cell carcinoma

D. Ureterocele



Malakoplakia is seen most commonly in


A. Kidney

B. Ureter

C. Bladder

D. Urethra



Most common site of Malakoplakia in G.I Tract


A. Stomach

B. Duodenum

C. Colon

D. Ileum



Share the Infographic



Most common site of Malakoplakia – GU tract, particularly bladder
Most common site of Malakoplakia in Gastrointestinal tract – colon, followed by stomach and duodenum


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