Heme synthesis

---

Incorporation of Fe2+ into the structure of protoporphyrin IX is catalyzed by

---

[A] Glutathione
[B] Hephaestin
[C] Haem oxidase
[D] Ferrochelatase

---

---

Heme synthesis

---

1. Fe2+ is incorporated in protoporphyrin IX with the help of the enzyme “ferrochelatase”
2. The final reaction of Heme synthesis is the incorporation of Fe2+ into the structure of protoporphyrin IX.
3. The process is catalyzed by ferrochelatase
4. Reaction takes place on the inner mitochondrial membrane

---