Heart failure cells

---

Heart failure cells are

---

A. Reticulocytes

B. Endothelial cells

C. Siderophages

D. Type II Pneumocytes

---

---

Siderophage is a hemosiderin-containing macrophage.

---

Heart failure cells are siderophages generated in the alveoli of the lungs of people with left heart failure or chronic pulmonary edema,

---

How the Heart Failure cells produced

---

Steps in formation of Heart Failure Cells

---

Heart Failure

1. – Pulmonary congestion
2. – High pulmonary blood pressure
3. – RBCs pass through vascular wall due to high pressure
4. – RBCs are phagocytized by alveolar macrophages

Alveolar macrophages (dust cells) engulf the red blood cells, and become engorged with brownish hemosiderin – Called Heart failure cells

---

Siderophages are seen in – pulmonary hemorrhage

---

Siderophages are not specific of heart failure. They are present wherever red blood cells encounter macrophages, such as pulmonary hemorrhage.

---