Heart failure cells
Heart failure cells are
B. Endothelial cells
D. Type II Pneumocytes
Siderophage is a hemosiderin-containing macrophage.
Heart failure cells are siderophages generated in the alveoli of the lungs of people with left heart failure or chronic pulmonary edema,
How the Heart Failure cells produced
Dteps in formation of Heart Failure Cells
- – Pulmonary congestion
- – High pulmonary blood pressure
- – RBCs pass through vascular wall due to high pressure
- – RBCs are phagocytized by alveolar macrophages
Alveolar macrophages (dust cells) engulf the red blood cells, and become engorged with brownish hemosiderin – Called Heart failure cells
Siderophages are seen in – pulmonary hemorrhage
Siderophages are not specific of heart failure. They are present wherever red blood cells encounter macrophages, such as pulmonary hemorrhage.