Ghost cells

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Ghost cells generally lack nuclear and cytoplasmic details and are characteristically seen in All of the following EXCEPT

[A] Calcifying cystic odontogenic tumor
[B] Craniopharyngiomas
[C] Giant cell tumor
[D] Pilomatricomas

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What is a ‘Ghost cell’?

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There is cell death with retainment of cellular architecture
Ghost cells indicate coagulative necrosis
They are dead cells

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They are found in:

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Craniopharyngioma (Rathke pouch)
Odontoma
Ameloblastic fibroma
Calcifying odontogenic cyst (Gorlin cyst)
Pilomatricoma

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Infarcted Lymph Node – Ghost cells

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• Usually result of involvement by lymphoma
• Vascular occlusion may explain necrosis
• Outlines of necrotic lymphoma cells (“ghost cells”)

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