“Fried-egg” appearance

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Fried egg appearance in dermatology is seen in –

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[A] Dysplastic Nevi
[B] Psoriasis
[C] Pemphigus vulgaris
[D] Angioblastoma

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	“Fried-egg” appearance	Cause
1	Fried-egg colony shape	Mycoplasmas
2	“Fried-egg” appearance microscopy	Brain Tumor – Oligodendroglioma
3	Ffried egg appearance in histopathology	Hairy cell leukemia (HCL)
4	”Fried-egg” appearance in Histology	Histologic features of the ”seminoma” & Dysgerminoma
5	Fried Egg Appearance (BM Biopsy) Bone marrow core biopsy, Plasma cells	Multiple Myeloma
6	Malassezia furfur being lipophilic, Sabouraud Dextrose Agar [SDA] with olive oil overlay is the ideal media for culture. Typical ‘fried egg‘ colonies appear	Malassezia furfur
7	Fried egg appearance in dermatology is seen in	Dysplastic Nevi

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“Fried-egg” appearance

• Oligodendroglioma – “Fried-egg” appearance microscopy – Brain Tumor
• Hairy cell leukemia (HCL) might be identified by the presence of distinct cell membrane and abundant clear cytoplasm, resulting in a “fried-egg” appearance.
• Seminoma and Dysgerminoma cells on light microscopy.
• Parietal cells of the stomach due to acidophilic cytoplasm & large central nuclei also resemble fried egg appearance.
• Malassezia furfur – Malassezia furfur being lipophilic, SDA with olive oil overlay is the ideal media for culture. Typical ‘fried egg‘ colonies appear
• Mycoplasma pneumoniae – produces tiny colonies on Eaton agar that have an “inverted fried egg” appearance.

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What is the morphology of Fried Egg appearance?

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