Enteric fever Diagnosis
Contents
Diagnosis in the first week is done by
A. Blood culture
B. Stool culture
C. Bone marrow culture
D. Widal test
Which is the gold standard for typhoid diagnosis?
A. Blood culture
B. Stool culture
C. Bone marrow culture
D. Widal test
In shorts
Diagnosis
Blood Culture – 1st Week
Widal Test – 2nd Week
Stool Culture – 3rd Week
Urine Culture – 4th Week
Widal Test
An antibody titer of greater than 1:160 and greater than 1:80 for anti-H antigen and anti-O antigen respectively are considered as cut off levels to predict recent infection of typhoid fever in an endemic area
Skin snip test
Skin snip test: Punch biopsies from characteristic rose spots may culture positive in up to 63% of the positive cases with prior therapeutic antibiotic treatment.
Intramuscular Vi capsular polysaccharide vaccine
Intramuscular Vi capsular polysaccharide vaccine is appropriate for those greater than two years old. It should be given 2 weeks or more before travel, and a booster should be provided every two years.
Oral vaccine [Ty21a strain of serotype Typhi] vaccine
A live attenuated oral vaccine (Ty21a strain of serotype Typhi) enhances immunity by stimulating the production of endogenous antibodies. It is indicated for those over 6 years old traveling to endemic areas or coming into close contact with chronic carriers or infected patients.
