Down syndrome – Pulmonary hypertension
Why individuals with Congenital heart disease associated due to Down Syndrome are more prone for pulmonary hypertension?
Genetic contributions to ALL of the following EXCEPT
[A] Abnormal lung development[B] Endothelial dysfunction
[C] Higher risk of Atherosclerosis
[D] Proinflammatory genes
- The rate of congenital heart disease in newborns with Down syndrome is around 40%.
- 80% have an atrial septal defect or ventricular septal defect
- ASD is commonest finding.
- People with Down syndrome have a lower risk of Atherosclerosis
