Down syndrome – genetic disorder

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Parents of the affected individual are usually

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[A] Genetically normal
[B] Genetically Mosaic
[C] Genetically have Robertsonian deletion
[D] Genetically haveTranslocation

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Down syndrome probability increases with

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[A] Increase in Paternal age
[B] Increase in Maternal age
[C] Increase in Early Marriage
[D] Decrease with Late Conception

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Extra chromosome in Down syndrome is provided at

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[A] Conception
[B] Embryo stage
[C] Mid gestation
[D] Late pregnancy

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Types of Down Syndrome

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• Trisomy 21 -Most Common
• Mosaic Down syndrome accounts for – two per cent of Down syndrome cases
• Translocation Down syndrome – accounts for three per cent of cases

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