Clinical Question-11

A 87-year-old man complained of a one-month history of a minimally pruritic rash on his abdomen, flanks, and buttocks.

His medical history revealed

  • Smoker [35 pack-years]
  • Chronic obstructive pulmonary disease
  • Non–small-cell carcinoma of the left upper lobe that was resected more than five years earlier.

A presumptive diagnosis of tinea corporis was made and treated accordingly.
After three months Reviewed –

  • showed no signs of improvement
  • weight loss over three months
  • “wood-grain” appearance of skin lesions seen
    What is the diagnosis?


  • Based on the patient’s history and physical examination, which of the following is the correct diagnosis?
    A. Erythema annulare centrifugum
    B. Mycosis fungoides (cutaneous T-cell lymphoma)
    C. Erythema marginatum
    D. Erythema gyratum repens


Erythema gyratum repens


  • Erythema gyratum repens is considered to be highly specific as paraneoplastic syndrome
  • Most common underlying neoplasms are from lung, breast, or esophagus
  • Some cases of erythema gyratum rapens–like eruptions are associated with infection (tuberculosis), connective tissue disease (lupus, Sjogren syndrome), or are idiopathic, but most cases are associated with a solid organ malignancy.
  • The most common neoplasm associated with erythema gyratum repens is lung carcinoma.

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